There's a good chance it wont be around for more than 5 years. You see, many executives absolutely hate traveling there. Same with St. Louis. Minneapolis is heading that direction too, but stands a much better chance than Des Moines does, which is why so many BUs are being scaled back in Des Moines but allowed to keep staff in Minnesota. I give it less than 5 years before at least 75% of jobs in Des Moines are gone. You'll be surprised at how fast it goes too. It will happen just like it did in Sioux Falls (which had more promise than Des Moines did). Watch for exec positions to leave first, then executives that want to keep their jobs, then everyone else.
Des Moines has always held itself in high regard - like San Francisco - but things are pushing east. You can forget about leasing or buying new properties in places like (LOL) Wyoming or Nevada as the previous poster mentioned - Won't happen. Big metropolitan areas with enough staff to cover the higher churn we will have is what they want these days. They will utilize existing buildings in those metropolitan areas/hubs and max out seating as much as they can instead.
Corporations are abandoning small towns, low population states, and metro areas they see as undesirable...which is pretty much everything west of the smokies outside of TX, CA, WA, etc.