Clean out your desk. Catch up on T&E and pay off AMEX. Take all vacation time owed to you. Clean out computer of any personal files. Type up transition notes. Put in your two weeks in writing. Depending on your job role & who you report to, they may shut you down immediately, OR may make you work the two weeks to help transition. In the old days, they would likely make a counter or at the very least make your feel very guilty and second guess leaving, but in today's climate with everybody ( & I mean everybody) worried about their jobs, more then likely one less head could mean more security for those who remain. Good luck to you.
This was reposted from @YDpu3v8-4uyo